Linear 1 3-diarylpropanoids
Medchemexpress LLC 1,3-Propanedione, 1,3-diphenyl- | 120-46-7 | 98.0% | 224.26 | 1 ML
Dibenzoylmethane is a minor ingredient in licorice that activates Nrf2, playing a role in preventing various cancers and oxidative damage. It acts as an analog of curcumin, causing dissociation from Keap1 and nuclear translocation of Nrf2. It is provided for research use only.
- Activates Nrf2 pathway
- Analog of curcumin
- Prevents cancers and oxidative damage
- Increases HO-1 and Nrf2 protein expression
- Protects against CCl4-induced liver damage in wild-type mice
Medchemexpress LLC Xanthohumol | 6754-58-1 | 354.40 | 1 ML
Xanthohumol is a principal flavonoid derived from hops, acting as an inhibitor of diacylglycerol acyltransferase (DGAT), COX-1, and COX-2. It exhibits anti-cancer and anti-angiogenic properties. Additionally, Xanthohumol demonstrates antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV).
- Inhibits diacylglycerol acyltransferase (DGAT), COX-1, and COX-2.
- Shows anti-cancer activities.
- Shows anti-angiogenic activities.
- Has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV).
Medchemexpress LLC Xanthohumol | 6754-58-1 | MFCD00210576 | 354.40 | 500 MG
Xanthohumol is one of the principal flavonoids isolated from hops, known for its inhibitory effects on diacylglycerol acetyltransferase (DGAT), COX-1, and COX-2. It demonstrates anti-cancer, anti-angiogenic, and antiviral activities against various viruses including bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV). This product is intended for research use only.
- Inhibitor of DGAT, COX-1, and COX-2
- Exhibits anti-cancer activity
- Possesses anti-angiogenic activity
- Shows antiviral activity against BVDV, rhinovirus, HSV-1, HSV-2, and CMV
- Appears as a yellow to orange solid
Medchemexpress LLC Xanthohumol | 6754-58-1 | MFCD00210576 | 99.3% | 354.40 g/mol | C21H22O5 | 10 MG
Xanthohumol (Standard) is an analytical reference standard of xanthohumol, a prenylated chalconoid flavonoid isolated from hops, supplied for research and analytical use in qualitative and quantitative assays and method development for HPLC, GC, and MS.
- Purity 99.30%.
- Molecular formula C21H22O5.
- Molecular weight 354.40 g/mol.
- Supplied as a solid, typically 10 mg.
- Intended for use as an analytical standard for HPLC, GC, and MS assays.
- Certificate of analysis provided; follow storage conditions in the CoA.
Medchemexpress LLC Xanthohumol C | 189299-05-6 | 99.2% | 352.38 | C21H20O5 | 10 MG
Xanthohumol C is a prenylchalcone natural product isolated from the hops plant Humulus lupulus. It is used in research and has reported cytotoxic and antiproliferative activity in human cancer cell lines.
- Chemical formula C21H20O5.
- Molecular weight 352.38.
- Purity 99.2%.
- Reported cytotoxicity against HeLa cells (IC50 12.5 μM).
- Antiproliferative activity against MCF7 cells (IC50 15.7 μM for 2 days, 6.87 μM for 4 days).
- Supplied as a 10 MG research quantity.
Medchemexpress LLC Xanthohumol C | 189299-05-6 | 352.38 | 5 MG
Xanthohumol C is a prenylchalcone that can be isolated from the hops of Humulus lupulus. It is categorized as a natural compound with a molecular weight of 352.38 and a chemical formula of C21H20O5. This compound appears as a light yellow to yellow solid and is intended for research use only, not for sale to patients.
- It is a prenylchalcone, a type of natural compound.
- It can be isolated from the hops of Humulus lupulus.
- It exhibits cytotoxicity against human HeLa cells with an IC50 of 12.5 μM.
- It shows antiproliferative activity against human MCF7 cells with IC50 values of 15.7 μM (2 days) and 6.87 μM (4 days).
Medchemexpress LLC Phlorizin | 60-81-1 | 99.9% | 436.41 | 5 G
Phlorizin is a non-selective SGLT inhibitor that acts on hSGLT1 and hSGLT2. It also functions as a Na+/K+-ATPase inhibitor.
- Non-selective SGLT inhibitor.
- Inhibits hSGLT1 and hSGLT2.
- Na+/K+-ATPase inhibitor.
- Decreases blood glucose levels.
- Prevents nerve fiber decrease and retinal abnormalities.
Medchemexpress LLC Phlorizin | 60-81-1 | MFCD00006652 | ≥98% | 436.43 | 1 G
Phlorizin is a biochemical reagent that acts as a non-selective SGLT inhibitor (hSGLT1 Ki: 300 nM, hSGLT2 Ki: 39 nM) and a Na+/K+-ATPase inhibitor. It is suitable for use as a biological material or organic compound in life science research.
- Non-selective SGLT inhibitor
- Na+/K+-ATPase inhibitor
- Classification: Flavonoids, Phenols, Polyphenols, Dihydrochalcones
- Source: Malus pumila Mill. (Rosaceae), Plants
- Targets: SGLT, Na+/K+ ATPase
- Research areas: Metabolic disease
TARGETMOL CHEMICALS INC 4-Hydroxychalcone 500MG
Also available in 5 g, 1 mL, 100 mg and bulk. Please contact Fisher for quotes. 4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity Purity 99.86%
Indofine Chemical Naringenin-7-O-Glucos, 10 Mg
NARINGENIN-7-O-GLUCOSIDE with HPLC, Flavonoid & Coumarins, 529-55-5, 99% by HPLC, 10 mg
Medchemexpress LLC AKT-IN-23 | 1226801-23-5 | 517.52 | 5 MG
AKT-IN-23 is an AKT inhibitor that can be used in cancer research. This product is designed for research use only and has not been fully validated for medical applications.
- Can be used in cancer research
- Inhibitor of AKT
Medchemexpress LLC Trans-chalcone | 614-47-1 | MFCD00003082 | 98.8% | 208.26 | C15H12O | 100g
trans-Chalcone isolated from Aronia melanocarpa skin is a biphenolic core structure of flavonoids precursor trans-Chalcone is a potent fatty acid synthase (FAS) and -amylase inhibitor trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7 trans-Chalcone has antifungal and anticancer activity[1][2][3]